If you’ve been giving your dog Adequan injections at home, you might have opened the news this week and felt your stomach drop. On July 31, 2026, American Regent Animal Health issued a nationwide recall of two specific lots of Adequan Canine Injection after glass fibers were found in the vials. This isn’t a precautionary “we think maybe possibly” situation. Glass fibers were detected during routine internal testing, and because Adequan is so commonly self-administered by pet owners at home, the FDA extended this recall all the way to the consumer level. That means affected vials could be sitting in your refrigerator right now.

Here’s what makes this especially urgent: the two recalled lots, lot numbers 3369 and 25011 (both 100 mg/mL, 5-mL multidose vials), have been in circulation for a long time. Lot 3369 was distributed nationwide on May 22, 2024. Lot 25011 went out on April 14, 2025. So we’re talking about vials that have potentially been in homes for anywhere from about fourteen months to over two years, according to the FDA recall announcement. If you’ve had a bottle sitting in the back of your fridge for a while, this is the moment to go check the lot number printed on the label.

As of the recall announcement, no adverse events had been reported, which is genuinely reassuring. But “no reports yet” doesn’t mean “no risk.” The FDA lists the potential consequences of injecting a glass-contaminated product as local irritation, swelling, inflammation, injection-site pain, infection, or abscess formation. Those are not small things, especially in a dog who’s already dealing with joint pain.

Key takeaways
  • Recalled lots are 3369 (distributed May 22, 2024) and 25011 (distributed April 14, 2025).
  • Both are 100 mg/mL, 5-mL multidose vials of Adequan Canine Injection.
  • Glass fiber contamination can cause injection-site infection, swelling, or abscess in dogs.
  • No adverse events had been reported as of July 31, 2026, but the recall extends to pet owners' homes.
  • Stop using affected vials immediately and contact your vet or the manufacturer before the next dose.

How to Check Your Vials Right Now

Go get the bottle. Seriously, do it before you keep reading. The lot number is printed on the label of the vial and on any outer packaging you may have kept. You’re looking for lot 3369 or lot 25011. If your vial shows either of those numbers, stop using it immediately, even if it looks perfectly clear. Glass fibers aren’t visible to the naked eye. A vial can look completely normal and still be contaminated.

If you’re unsure how to find the lot number, it’s typically a sequence of numbers near the expiration date. It may be preceded by the word “Lot” or “LOT.” If you’ve already discarded the packaging and can’t read the label clearly, err on the side of caution and call your veterinary clinic before the next scheduled injection.

What the Recall Means for Your Dog’s Treatment

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This part is where things get genuinely complicated, and I want to be honest with you about it. Adequan Canine is the only FDA-approved disease-modifying osteoarthritis drug for dogs. It’s not just a pain reliever. It works at the joint level to slow cartilage breakdown, and for many dogs with degenerative joint disease, it’s doing real work that no other injectable product is currently approved to replicate. There’s no direct drop-in substitute, as dvm360 noted in their coverage of the recall.

Missing a few doses isn’t going to undo everything Adequan has done for your dog. But if your dog has been on a maintenance protocol and you’re suddenly without medication, here’s what I tell people: call your vet clinic Monday morning (or today if they have weekend hours) and explain the situation. They may have unaffected lot numbers in stock, or they can help you prioritize what to do next based on where your dog is in their treatment plan. Some dogs on maintenance schedules have more flexibility than others. Your vet knows your dog’s case and can give you guidance that’s specific to them.

Recall DetailLot 3369Lot 25011
Distribution dateMay 22, 2024April 14, 2025
Time in circulation~26 months~15 months
ProductAdequan Canine 100 mg/mL, 5-mL vialAdequan Canine 100 mg/mL, 5-mL vial
ScopeNationwideNationwide
Adverse events reportedNone as of July 31, 2026None as of July 31, 2026

Signs to Watch For If Your Dog Has Already Received a Recalled Lot

If you’ve been using one of the recalled lot numbers and your dog has already had injections from it, take a breath. The good news is that no injuries have been reported so far. But you should be watching the injection sites. For the next several days, check the area where the shot was given for any swelling, redness, warmth, or a lump that wasn’t there before. Watch for your dog flinching when you touch the area, or any change in appetite or energy that seems sudden and unexplained.

A small amount of tenderness right after an injection is normal. What’s not normal is a lump that grows, skin that feels hot, or discharge from the injection site. Those are signs of a possible abscess or infection, and that’s a same-day veterinary visit, not a wait-and-see situation.

If you want to report a suspected adverse event, the FDA’s MedWatch program accepts reports from pet owners, as does the manufacturer. Your vet can also submit a report on your behalf, and I’d encourage you to loop them in regardless, especially if your dog has received multiple injections from a recalled lot.

What to Do With the Recalled Vials

Don’t just toss them in the trash, and please don’t pour the contents down the drain. American Regent Animal Health is the contact for questions about returns and reimbursement. Their information should be included in any recall notice you receive from your pharmacy or clinic, and it’s also available through the FDA recall page. Fox Business reported on the recall as of August 5, 2026, and noted the scope included both dog and horse formulations, so if you have multiple animals on Adequan products, check all of them.

Keep the vial intact and store it away from any other medications while you sort out the return process. Your vet clinic or pharmacy may be able to facilitate the return, or they can point you to the right contact. Don’t feel embarrassed to ask. This is exactly the kind of situation clinics field all the time.

The recall is unsettling, particularly for people who’ve built a careful routine around managing their dog’s arthritis. One missed dose isn’t a crisis. What matters now is checking your lot numbers, stopping use if you’re affected, and reaching out to your vet before that next injection date. Your dog’s joints can wait a day or two for a phone call. They shouldn’t wait through injections from a compromised vial.

Sources

Photo: Tima Miroshnichenko via Pexels

This article is for general informational purposes only and does not constitute veterinary advice. Pet health symptoms can have many causes and require professional evaluation. Always consult a licensed veterinarian for diagnosis and treatment specific to your pet.

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